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瑞典乌普萨拉大学博士后职位

时间:2019-02-21来源:中国博士人才网 作者:佚名

 职位描述:

  我们邀请了瑞典乌普萨拉大学免疫学,遗传学和病理学系(IGP)血管生物学部门PontusAspenström研究小组的任命申请。该研究小组正在研究Rho GTPases的Ras样家族,它们是肌动蛋白丝系统的关键调节因子,从而控制重要的细胞过程,如细胞形态发生,细胞极性和细胞迁移。

  该研究旨在阐明健康和疾病中Rho依赖的信号传导机制。一组项目专注于Miro GTPases,它是线粒体稳态和功能的关键参与者。它们在生理环境中的重要性也使它们成为神经退行性疾病病理学中的重要蛋白质。

  另一组项目集中于所谓的非典型Rho GTPases的作用,Rho GTPases是Rho GTPases的一个亚类,用于治疗恶性间皮瘤和胶质母细胞瘤。主要目的是阐明非典型Rho GTP酶在癌细胞迁移和转移中脱轨功能背后的机制,并确定药物治疗的新靶点。乌普萨拉大学免疫学,遗传学和病理学系(www.igp.uu.se )与几个国际强大的研究小组有广泛的研究概况。乌普萨拉大学是瑞典财团SciLifeLab.se(www.scilifelab.se)的一部分,该联盟为高级生命科学研究提供最先进的基础设施,包括化学生物学,药物发现和开发以及先进光学显微镜平台。

  资格:

  我们正在寻找一位积极进取,才华横溢,受过良好教育的研究人员,在过去三年中,他在细胞生物学,神经科学或相关研究课题中获得博士学位。

  优点:

  申请人应具有分子细胞生物学的强大背景和先进细胞生物学技术的实践经验,包括显微镜和成像,是先决条件。候选人应具备出色的协作技能和国际研究经验

  环境。

  奖学金/工资:在获得博士学位或同等学历后的四年内,可以授予进行博士后研究的奖学金最多两年。该教育奖学金免税。该金额一次设定为12个月,并按月支付。

  申请:申请表必须包含以下英文文件:

  1。履历和资格

  2。完整的出版物清单。

  3.一封信,描述了加入该组织的动机以及当前研究的简要总结(1-2页)。

  4。两名参考人员的联系方式。

  申请将根据资格要求,相关研究领域的成就和个人适用性进行评估。

  欲了解更多信息,请联系PontusAspenström,pontus.aspenstrom @ upp.uu.se。我们拒绝提供招聘和广告帮助。我们只按照广告中描述的方式接受申请。

  英文原文:

  We invite applications for a postdoctoral appointment in the research group of Pontus Aspenström, in the Vascular Biology Unit at the Dept. of Immunology, Genetics and Pathology (IGP), Uppsala University, Sweden. The research group is studying the Ras-like family of Rho GTPases,which are key regulators of the actin filament system and thereby control vital cellular processes such as cell morphogenesis, cell polarity and cell migration.

  The research is aimed to elucidate the Rho-dependent signalling mechanisms in health and disease. One set of projects focus on the Miro GTPases, which are key players in mitochondrial homeostasis and functioning. Their importance in a physiological context also makes them significant proteins in the pathology of neurodegenerative diseases.

  Another set of projects focus on the role of the so-called atypical Rho GTPases, which is a subclass of the Rho GTPases, in malignant mesothelioma and glioblastoma。 The principal goal is to elucidate the mechanisms behind the derailed function of atypical Rho GTPases in cancer cell migration and metastasis and to identify new targets for drug treatment。The Department of immunology, genetics and pathology at Uppsala University (www。igp。uu。se) has a broad research profile with several internationally strong research groups。 Uppsala University is part of a Swedish consortium,SciLifeLab。se (www。scilifelab。se), which provides state-of the art infrastructure for advanced life science research including platforms for Chemical Biology, Drug Discovery and Development, and Advanced Light Microscopy。

  Qualifications:

  We are seeking a highly motivated, talented and well-educated researcher with a PhD degree awarded within the past three years in cell biology, neuroscience or in a related research topic.

  Merits:

  The applicant should have a strong background in molecular cell biology and practical experience of advanced cell biology techniques, including microscopy and imaging, is a prerequisite. The candidate should have excellent collaboration skills and experience in working in an international research

  environment。

  Scholarship/salary: Ascholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent. This educational scholarship is tax-exempt. The amount is set for twelve months at a time and is paid out on a monthly basis.

  Application: An application must contain the following documents in English:

  1。Curriculum vitae and qualifications

  2。 A complete list of publications。

  3. A letter describing the motivation to join the group and a brief summary of current research (1-2 pages).

  4。 Contact details for two reference persons。

  The applications will be assessed based on eligibility requirements,achievements in related research areas, and personal suitability.

  For more information, contact Pontus Aspenström, pontus.aspenstrom@igp.uu.se.We decline offers of recruitment and advertising help. We only accept the application the way described in the advertisement.

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